The final trades of the day with CNBC's Melissa Lee and the 'Fast Money' traders.

Gradient Investments senior portfolio manager Keith Gangl shares some of his top stock picks he is predicting for 2026, like Amazon, TJX Companies, and Cintas. Also hear Keith Gangl address how geopolitical headlines and policy proposals are creating more "noise" for investors right now.

Amazon has launched an artificial intelligence (AI) assistant for its One Medical app. The agentic AI tool, announced Wednesday (Jan. 21), is designed to help with things like answering health questions, scheduling appointments and managing medications.

Jeff Bezos-backed Blue Origin is launching a satellite internet network for enterprise, data center and government customers, called TeraWave. The company aims to begin deploying the first of 5,408 satellites in the fourth quarter of 2027.

Amazon's 2025 capital expenditures were the highest in the company's history. Investors have grown impatient with the lack of tangible results from that spending.

Amazon.com, Inc.'s underwhelming stock performance in recent years could change course in 2026. Question regarding long-term AMZN profitability and return on capital of AI investments remain, but this is less likely to be the main topic in 2026. There are two main caveats when it comes to AMZN being a Buy, and investors should plan their purchases of the stock accordingly.

Amazon is seeing great operating leverage in its e-commerce business. Growth at AWS is starting to accelerate.

Amazon leans on emerging markets for growth as international revenues rise, profitability improves and logistics scale across India and Latin America.

Amazon is rolling out an artificial intelligence health-care tool for One Medical members, called Health AI. The service uses large language models and references patients medical records to answer questions, manage medications and book appointments.

Major US stocks are looking for some type of bullish behavior via the headlines and macro outlook to get moving on Wednesday.